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HTML5基本構造 HTML5の基礎組み立て DOCTYPE 宣言（DOCTYPE スイッチ） HTML5基本構造 参考サイト：http //www.htmq.com/html5/002.shtml より明確に文書構造を示すことができる フォームの入力補助やチェック機能を属性で指定できる 動画や音声データをHTMLからシンプルに扱える APIの追加により、ウェブアプリケーションが構築しやすくなる HTML5で追加される予定の要素（タグ） HTML5で廃止される予定の要素（タグ） HTML5の基礎組み立て !DOCTYPE html html lang="ja" head title TAG Design /title !-- 文字コード -- meta http-equiv="Content-Type" content="text/html; charset=utf-8" !-- 検索キーワード -- meta name="keywords" content="keyword1,keyword2" !-- サイト説明文 -- meta name="description" content="This is test page !" !-- 作者情報 -- meta name="author" content="miyoshi" !-- 著作権情報 -- meta name="copyright" content="miyoshi" !-- css外部参照 -- link rel="stylesheet" type="text/css" href="../css/style.css" !-- google api - jquery -- script type="text/javascript" src="https //ajax.googleapis.com/ajax/libs/jquery/1.7.2/jquery.min.js" /script /head body div id="wrapper" header h1 TAG Design /h1 h2 ~ tag design ~ /h2 /header div id="main" ul li class="about" a href="#" About Us /a /li /ul /div footer li a href="#" 個人情報の取り扱いについて /a /li li a href="#" サイトマップ /a /li p Copyright copy; 2012 TAG Design /p /footer /div /body /html DOCTYPE 宣言（DOCTYPE スイッチ） 参考サイト：http //2xup.org/log/2007/07/27-2111 各ブラウザの DOCTYPE スイッチ対応表：http //spreadsheets.google.com/pub?key=pbrvd2wQKc03fJ5QWgYr-Cw gid=3 HTML5はDTDがいらない：http //withd.jp/web/tips/standard/3947.html?page=2 DTDwiki：http //ja.wikipedia.org/wiki/Document_Type_Definition オンの状態 standards mode (標準準拠モード) 仕様に準拠した厳格な表示モード オフの状態 quirks mode (後方 (過去) 互換モード) 仕様に準拠していない古いブラウザとの互換 css3フォーマット @import url(http //fonts.googleapis.com/css?family=Fredericka+the+Great); body, header, nav, article, aside, footer, div, ul, li, h1, h2, p { margin 0; padding 0; } body { text-align center; line-height 1.5; min-width 800px; background-color #f5f5f1; color #666666; font-family Fredericka the Great , cursive; font-size 62.5%; }
https://w.atwiki.jp/metalmetabo/pages/30.html
- visitors Metabolic pathway analysis of enzyme-deficient human red blood cells T ÇakIr, CS Tacer, KÖ Ülgen - Biosystems, 2004 - Elsevier http //scholar.google.com/scholar?q=related 8w1qIgoYqGcJ scholar.google.com/ hl=ja as_sdt=2000 Five enzymopathies (G6PDH, TPI, PGI, DPGM and PGK deficiencies) in the human red blood cells are investigated using a stoichiometric modeling approach, ie, metabolic pathway analysis. Elementary flux modes (EFMs) corresponding to each enzyme deficiency case ... Reconstruction of metabolic networks from genome data and analysis of their global structure for various organisms oxfordjournals.org [PDF]H Ma, AP Zeng - Bioinformatics, 2003 - Oxford Univ Press http //scholar.google.com/scholar?q=related SuHZgSLeNw8J scholar.google.com/ hl=ja as_sdt=2000 Page 1. BIOINFORMATICS Vol. 19 no. 2 2003 Pages 270–277 Reconstruction of metabolic networks from genome data and analysis of their global structure for various organisms Hongwu Ma1, 2 and An-Ping Zeng1,∗ 1GBF ... Elementary mode analysis a useful metabolic pathway analysis tool for characterizing cellular metabolism CT Trinh, A Wlaschin, F Srienc - Applied microbiology and biotechnology, 2009 - Springer http //scholar.google.com/scholar?q=related hkaWpJnxK5QJ scholar.google.com/ hl=ja as_sdt=2000 Abstract Elementary mode analysis is a useful metabolic pathway analysis tool to identify the structure of a metabolic network that links the cellular phenotype to the corresponding genotype. The analysis can decompose the intricate metabolic network comprised of ... Extreme pathway analysis of human red blood cell metabolism nih.gov [PDF]SJ Wiback, BO Palsson - Biophysical Journal, 2002 - Elsevier http //scholar.google.com/scholar?q=related hVaLEfzPgSEJ scholar.google.com/ hl=ja as_sdt=2000 Constraints-based models regulation of gene expression reduces the steady-state solution space MW Covert, BO Palsson - Journal of theoretical Biology, 2003 - Elsevier http //scholar.google.com/scholar?q=related o9VRtN2gAKQJ scholar.google.com/ hl=ja as_sdt=2000 ... Biol. 203, 249, 283. 26. CH SCHILLING, S. SCHUSTER, BO PALSSON and R.HEINRICH, Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15 (1999), pp. 296–303. ... The JAK-STAT signaling network in the human B-cell an extreme signaling pathway analysis nih.gov [HTML]JA Papin, BO Palsson - Biophysical Journal, 2004 - Elsevier http //scholar.google.com/scholar?q=related myiNLachV-QJ scholar.google.com/ hl=ja as_sdt=2000 From genome to cellular phenotype—a role for metabolic flux analysis? A Cornish-Bowden, ML Cárdenas - Nature Biotechnology, 2000 - nature.com http //scholar.google.com/scholar?q=related Q1z877WO_uAJ scholar.google.com/ hl=ja as_sdt=2000 ... whether a bypass exists within a complex network. Metabolic pathway analysis aims to identify indispensable enzymes, thus predicting the effects of their deletion or inhibition. Flux analysis should also allow the determination ... On-line metabolic pathway analysis based on metabolic signal flow diagram H Shi, K Shimizu - Biotechnology and bioengineering, 1998 - interscience.wiley.com http //scholar.google.com/scholar?q=related wjDdrq_SGcQJ scholar.google.com/ hl=ja as_sdt=2000 Abstract In this work, an integrated modeling approach based on a metabolic signal flow diagram and cellular energetics was used to model the metabolic pathway analysis for the cultivation of yeast on glucose. This ap- proach enables us to make a clear analysis of the flow ... Metabolic pathway analysis of recombinant Saccharomyces cerevisiae with a galactose-inducible promoter based on a signal flow modeling approach S Jin, K Ye, K Shimizu - Journal of Fermentation and Bioengineering, 1995 - Elsevier http //scholar.google.com/scholar?q=related 0uzMsbsJrXEJ scholar.google.com/ hl=ja as_sdt=2000 The objective of this work was to develop a signal flow diagram-based modeling approach proposed by Endo et al. (1976) to organize the network of complex metabolic reactions occurring in the living cell, employing directed signal flow diagram in which the enzyme reaction ... Energy balance for analysis of complex metabolic networks nih.gov [PDF]DA Beard, S Liang, H Qian - Biophysical journal, 2002 - Elsevier http //scholar.google.com/scholar?q=related wcAvs5fp3FgJ scholar.google.com/ hl=ja as_sdt=2000
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Versailles Official Web Site - TOUR Versailles-Philharmonic Quintet- MySpace BACKSTAGE PROJECT Versailles World Tour 2010 Venue Maps CD Japan - Official concert goods / CD, DVD, magazines All items JAPAN Discoveries - Official concert goods CD, DVD, magazines d-photo.tv - Official members' photos Versailles Fan CommunityThe site administrator gave us forums!! Let s share excited Versailles concerts!! 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https://w.atwiki.jp/metalmetabo/pages/32.html
- visitors Development of network-based pathway definitions the need to analyze real metabolic networks nhahocotton.org.vn [PDF]BO Palsson, ND Price, JA Papin - Update, 2003 - nhahocotton.org.vn http //scholar.google.com/scholar?q=related RJrIZTi52eQJ scholar.google.com/ hl=ja as_sdt=2000 ... A recent article [1] addresses the important issue of network-based metabolic pathway analysis. ... References 1 Klamt, S. and Stelling, J. (2003) Two approaches for metabolic pathway analysis? Trends Biotechnol. 21, 64–69 2 Karp, PD et al. ... PathFinder reconstruction and dynamic visualization of metabolic pathways oxfordjournals.org [PDF]A Goesmann, M Haubrock, F Meyer, J … - …, 2002 - Oxford Univ Press http //scholar.google.com/scholar?q=related tN609hXVn9QJ scholar.google.com/ hl=ja as_sdt=2000 ... database. Nucleic Acids Res., 26, 43–45. Tohsato,Y., Matsuda,H. and Hashimoto,A.(2000) A multiple align- ment algorithm for metabolic pathway analysis using enzyme hierarchy. Proceedings, ISMB 2000. pp. 376–383. Wackett ... Toward metabolic phenomics analysis of genomic data using flux balances dss.go.th [PDF]CH Schilling, JS Edwards, BO … - Biotechnology progress, 1999 - Wiley Online Library http //scholar.google.com/scholar?q=related 5xFNmiGLuFoJ scholar.google.com/ hl=ja as_sdt=2000 ... This approach of metabolic pathway analysis accompanied with FBA techniques can allow one to assess the basic structural capabilities and fitness of an organism as a result of the pathways that are theoretically present within the cell. ... Robustness Analysis of the Escherichiacoli Metabolic Network dss.go.th [PDF]JS Edwards, BO Palsson - Biotechnology Progress, 2000 - interscience.wiley.com http //scholar.google.com/scholar?q=related F73ImcZpznMJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. Robustness Analysis of the Escherichia coli Metabolic Network Jeremy S.Edwards† and Bernhard O. Palsson* Department of Bioengineering, University of California-San Diego, La Jolla, California 92093-0412 Genomic ... FluxAnalyzer exploring structure, pathways, and flux distributions in metabolic networks on interactive flux maps oxfordjournals.org [PDF]S Klamt, J Stelling, M Ginkel, ED Gilles - Bioinformatics, 2003 - Oxford Univ Press http //scholar.google.com/scholar?q=related vOydM3d06iMJ scholar.google.com/ hl=ja as_sdt=2000 ... additionally reversibility and capacity restrictions for each reaction. Metabolic Pathway Analysis (MPA) searches for meaningful structural and functional units in metabolic networks. The two most promising, very similar ap- proaches ... Integrating cybernetic modeling with pathway analysis provides a dynamic, systems-level description of metabolic control JD Young, KL Henne, JA Morgan, AE … - Biotechnology and …, 2008 - interscience.wiley.com http //scholar.google.com/scholar?q=related SiQjLbrsCw4J scholar.google.com/ hl=ja as_sdt=2000 ... biochemical networks. Combining cybernetic control laws with concepts from metabolic pathway analysis has culminated in a sys- tematic strategy for constructing cybernetic models, which was previously lacking. The newly ... Exploring the pathway structure of metabolism decomposition into subnetworks and application to Mycoplasma pneumoniae oxfordjournals.org [PDF]S Schuster, T Pfeiffer, F Moldenhauer, I Koch, T … - …, 2002 - Oxford Univ Press http //scholar.google.com/scholar?q=related o1Qpi78HxmoJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. BIOINFORMATICS Vol. 18 no. 2 2002 Pages 351–361 Exploring the pathway structure of metabolism decomposition into subnetworks and application to Mycoplasma pneumoniae S. Schuster 1 , T. Pfeiffer 2 , F. Moldenhauer 1 , I. Koch 3 and T. Dandekar 4, 5 ... The complete genome sequence of the gastric pathogen Helicobacter pylori JF Tomb, O White, AR Kerlavage, RA Clayton, GG … - Nature, 1997 - nature.com http //scholar.google.com/scholar?q=related Eo36dy8hFLcJ scholar.google.com/ hl=ja as_sdt=2000 ... Top of page Metabolism. Metabolic pathway analysis of the H. pylori genome suggests the following features. H. pylori uses glucose as the only source of carbohydrate and the main source for substrate-level phosphorylation. ... Deriving phylogenetic trees from the similarity analysis of metabolic pathways oxfordjournals.org [PDF]M Heymans, AK Singh - Bioinformatics, 2003 - Oxford Univ Press http //scholar.google.com/scholar?q=related Y2vvexN5fz8J scholar.google.com/ hl=ja as_sdt=2000 Page 1. BIOINFORMATICS Vol. 19 Suppl. 1 2003, pages i138–i146 DOI 10.1093/bioinformatics/btg1018 Deriving phylogenetic trees from the similarity analysis of metabolic pathways Maureen Heymans and Ambuj K. Singh ∗ ... Treatment of multifunctional enzymes in metabolic pathway analysis S Schuster, I Zevedei-Oancea - Biophysical chemistry, 2002 - Elsevier http //scholar.google.com/scholar?q=related G_O7SiZhvKsJ scholar.google.com/ hl=ja as_sdt=2000 In metabolic pathway analysis, it should be considered that many enzymes operate with low specificity (eg nucleoside diphosphokinase, uridine kinase, transketolase, aldolase), so that various substrates and products can be converted. Here, we analyze the effect of ...
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[HTML] ヘッダ部記述 !DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0//EN" HTML HEAD META HTTP-EQUIV="Pragma" CONTENT="no-cache" META HTTP-EQUIV="Cache-Control" CONTENT="no-cache,must-revalidate" META HTTP-EQUIV="Expires" CONTENT="0" META HTTP-EQUIV="Content-type" CONTENT="text/html; charset=Shift_JIS" TITLE ページタイトル /TITLE /HEAD [HTML] 表示バー table width="480" border="0" cellspacing="0" cellpadding="5" tr td height="50" width="15" bgcolor="#0000CC" /td td height="50" width="385" bgcolor="#CCCCFF" font size="3" b こんな感じで表示 /b /font /td /tr /table [HTML]作成者フッター TABLE WIDTH="100%" BORDER="0" CELLSPACING="0" CELLPADDING="0" TR TD ALIGN="RIGHT" HR Copyright(C)なんとか会社, Ltd. 2008. All rights reserved. /TD /TR /TABLE
https://w.atwiki.jp/metalmetabo/pages/26.html
- visitors Combining pathway analysis with flux balance analysis for the comprehensive study of metabolic systems slu.edu [PDF]… JS Edwards, D Letscher, BØ Palsson - Biotechnology and …, 2000 - interscience.wiley.com http //scholar.google.com/scholar?q=related HtFdZ3DFTgMJ scholar.google.com/ hl=ja as_sdt=2000 ... dimensional space. From metabolic pathway analysis, the edges of the high-dimensional flux cone are vectors that correspond to sys- temically defined “extreme pathways” spanning the ca- pabilities of the system. The addition ... Metabolic pathway analysis of yeast strengthens the bridge between transcriptomics and metabolic networks T Çakir, B Kirdar, KÖ Ülgen - Biotechnology and …, 2004 - Wiley Online Library http //scholar.google.com/scholar?q=related cUtrabByB40J scholar.google.com/ hl=ja as_sdt=2000 Abstract Central carbon metabolism of the yeast Saccha- romyces cerevisiae was analyzed using metabolic pathway analysis tools. Elementary flux modes for three substrates (glucose, galactose, and ethanol) were determined using the catabolic reactions ... Metabolic pathway analysis for rational design of L-methionine production by Escherichia coli and Corynebacterium glutamicum JO Krömer, C Wittmann, H Schröder, E Heinzle - Metabolic engineering, 2006 - Elsevier http //scholar.google.com/scholar?q=related KSxlsQoF_oIJ scholar.google.com/ hl=ja as_sdt=2000 Metabolic pathway analysis was carried out to predict the metabolic potential of Corynebacterium glutamicum and Escherichia coli for the production of L-methionine. Based on detailed stoichiometric models for these organisms, this allowed the calculation of the theoretically optimal ... The genome-scale metabolic extreme pathway structure in Haemophilus influenzae shows significant network redundancy JA Papin, ND Price, JS Edwards, BØ … - Journal of theoretical …, 2002 - Elsevier http //scholar.google.com/scholar?q=related KrUkw9kndisJ scholar.google.com/ hl=ja as_sdt=2000 ... 229–248. Abstract | PDF (428 K) | View Record in Scopus | Cited By in Scopus (198). 19. CHSCHILLING, S. SCHUSTER, BO PALSSON and R. HEINRICH, Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. ... Potential drug targets in Mycobacterium tuberculosis through metabolic pathway analysis psu.edu [PDF]S Anishetty, M Pulimi, G Pennathur - Computational Biology and …, 2005 - Elsevier http //scholar.google.com/scholar?q=related hEJbAmAPhwkJ scholar.google.com/ hl=ja as_sdt=2000 The emergence of multidrug resistant varieties of Mycobacterium tuberculosis has led to a search for novel drug targets. We have performed an insilico comparative analysis of metabolic pathways of the host Homo sapiens and the pathogen M. tuberculosis. Enzymes from the ... In silico metabolic pathway analysis and design succinic acid production by metabolically engineered Escherichia coli as an example jsbi.org [PDF]SY Lee, SH Hong, SY Moon - GENOME INFORMATICS SERIES, 2002 - jsbi.org http //scholar.google.com/scholar?q=related 6Ehoy39R1HUJ scholar.google.com/ hl=ja as_sdt=2000 Abstract The intracellular metabolic fluxes can be calculated by metabolic flux analysis, which uses a stoichiometric model for the intracellular reactions along with mass balances around the intra- cellular metabolites. In this study, we have constructed in silico metabolic pathway ... Determination of redundancy and systems properties of the metabolic network of Helicobacter pylori using genome-scale extreme pathway analysis cshlp.org [HTML]ND Price, JA Papin, BØ Palsson - Genome Research, 2002 - genome.cshlp.org http //scholar.google.com/scholar?q=related hyQpOmehsTYJ scholar.google.com/ hl=ja as_sdt=2000 Metabolic pathway analysis in trypanosomes and malaria parasites. nih.gov [PDF]AH Fairlamb - Philosophical Transactions of the Royal Society B …, 2002 - ncbi.nlm.nih.gov http //scholar.google.com/scholar?q=related x44FtcJTlQwJ scholar.google.com/ hl=ja as_sdt=2000 Identification of novel drug targets is required for the development of new classes of drugs to overcome drug resistance and replace less efficacious treatments. In theory, knowledge of the entire genome of a pathogen identifies every potential drug target in any given microbe. ... A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks uni-erlangen.de [PDF]S Schuster, DA Fell, T Dandekar - Nature biotechnology, 2000 - nature.com http //scholar.google.com/scholar?q=related 4GmcRTKIXlwJ scholar.google.com/ hl=ja as_sdt=2000 ... Trends Biotechnol. 17, 53–60(1999). | Article | PubMed | ISI | ChemPort |; Schilling, CH, Schuster, S., Palsson, BO Heinrich R. Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15, 296–303 (1999). ...
https://w.atwiki.jp/metalmetabo/pages/20.html
- visitors Sulfurtransferases 2010 Cell Biology of Molybdenum F Bittner, RR Mendel - Cell Biology of Metals and Nutrients, 2010 - Springer http //scholar.google.co.jp/scholar?q=related 1fBydctAk0cJ scholar.google.com/ hl=ja as_sdt=2000 Abstract The transition element molybdenum (Mo) is essential for (nearly) all biological systems as it is required by enzymes catalyzing diverse key reactions in the global carbon, sulfur,and nitrogen metabolism. The metal itself is biologically inactive unless it is complexed by a ... 2009 Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions nih.gov [HTML]A Noma, Y Sakaguchi, T Suzuki - Nucleic Acids Research, 2009 - Oxford Univ Press http //scholar.google.co.jp/scholar?q=related kS8aGPMvT5kJ scholar.google.com/ hl=ja as_sdt=2000 The wobble modification in tRNAs, 5-methoxycarbonylmethyl-2-thiouridine (mcm 5 s 2 U), is required for the proper decoding of NNR codons in eukaryotes. The 2-thio group confers conformational rigidity of mcm 5 s 2 U by largely fixing the C3 -endo ribose puckering, ensuring stable ... Origin and function of ubiquitin-like proteins nih.gov [HTML]M Hochstrasser - Nature, 2009 - nature.com http //scholar.google.co.jp/scholar?q=related vqhk3w9krT0J scholar.google.com/ hl=ja as_sdt=2000 Eukaryotic proteins can be modified through attachment to various small molecules and proteins. One such modification is conjugation to ubiquitin and ubiquitin-like proteins (UBLs), which controls an enormous range of physiological processes. Bound UBLs ... 2008 Molybdoproteomes and evolution of molybdenum utilization nih.gov [HTML]Y Zhang, VN Gladyshev - Journal of molecular biology, 2008 - Elsevier http //scholar.google.co.jp/scholar?q=related g2yHxFnhe4AJ scholar.google.com/ hl=ja as_sdt=2000 as_ylo=1981 as_yhi=2010 The trace element molybdenum (Mo) is utilized in many life forms, and it is a key component of several enzymes involved in nitrogen, sulfur, and carbon metabolism. With the exception of nitrogenase, Mo is bound in proteins to a pterin, thus forming the molybdenum cofactor ( ... Common thiolation mechanism in the biosynthesis of tRNA thiouridine and sulphur-containing cofactors nih.gov [HTML]N Shigi, Y Sakaguchi, S Asai, T Suzuki, K … - The EMBO Journal, 2008 - nature.com http //scholar.google.co.jp/scholar?q=related ARSfgx3Fp70J scholar.google.com/ hl=ja as_sdt=2000 as_ylo=2001 as_yhi=2010 2-Thioribothymidine (s 2 T), a modified uridine, is found at position 54 in transfer RNAs (tRNAs) from several thermophiles; s 2 T stabilizes the L-shaped structure of tRNA and is essential for growth at higher temperatures. Here, we identified an ATPase (tRNA-two-thiouridine ... The Sulfurtransferase Activity of Uba4 Presents a Link between Ubiquitin-like Protein Conjugation and Activation of Sulfur Carrier Proteins† J Schmitz, MM Chowdhury, P Hänzelmann, M … - Biochemistry, 2008 - ACS Publications http //scholar.google.co.jp/scholar?q=related tu5O65itnDEJ scholar.google.com/ hl=ja as_sdt=2000 as_ylo=2001 as_yhi=2010 Because of mechanistic parallels in the activation of ubiquitin and the biosynthesis of several sulfur-containing cofactors, we have characterized the human Urm1 and Saccharomyces cerevisiae Uba4 proteins, which are very similar in sequence to MOCS2A and MOCS3, respectively, ... Thio-modification of yeast cytosolic tRNA requires a ubiquitin-related system that resembles bacterial sulfur transfer systems jbc.org [HTML]Y Nakai, M Nakai, H Hayashi - Journal of Biological Chemistry, 2008 - ASBMB http //scholar.google.co.jp/scholar?q=related rEPGgeDDU4AJ scholar.google.com/ hl=ja as_sdt=2000 The wobble uridine in yeast cytosolic tRNA Lys2 UUU and tRNA Glu3 UUC undergoes a thio-modification at the second position (s 2 modification) and a methoxycarbonylmethyl modification at the fifth position (mcm 5 modification). We previously demonstrated that the cytosolic ... An embarrassment of riches the enzymology of RNA modification nih.gov [HTML]D Iwata-Reuyl - Current opinion in chemical biology, 2008 - Elsevier http //scholar.google.co.jp/scholar?q=related 0tsj3spLBLEJ scholar.google.com/ hl=ja as_sdt=2000 The maturation of transfer RNA (tRNA) involves extensive chemical modification of the constituent nucleosides and results in the introduction of significant chemical diversity to tRNA. Many of the pathways to these modified nucleosides are characterized by chemically complex ... A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae cshlp.org [HTML]B Huang, J Lu, AS Byström - Rna, 2008 - rnajournal.cshlp.org http //scholar.google.co.jp/scholar?q=related 4xQVocA9SD4J scholar.google.com/ hl=ja as_sdt=2000 We recently showed that the γ-subunit of Kluyveromyces lactis killer toxin (γ-toxin) is a tRNA endonuclease that cleaves , , and 3′ of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine (mcm 5 s 2 U). The 5-methoxycarbonylmethyl ... 2007 Biosynthesis of the Thio-quinolobactin Siderophore an Interesting Variation on Sulfur Transfer nih.gov [HTML]AM Godert, M Jin, FW McLafferty, TP … - Journal of …, 2007 - Am Soc Microbiol http //scholar.google.co.jp/scholar?q=related EBTZm24E50AJ scholar.google.com/ hl=ja as_sdt=2000 Text 15 Thio-quinolobactin, 8-hydroxy-4-methoxy-thioquinaldic acid (structure 1), is a 16 ... 17400.(10-12) The genes responsible for the biosynthesis of thio-quinolobactin have 18 ... There are a number of naturally occurring molecules of diverse structure that 27 A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast cshlp.org [HTML]GR Björk, B Huang, OP Persson, AS Byström - Rna, 2007 - rnajournal.cshlp.org http //scholar.google.co.jp/scholar?q=related ufP8yaCqiVsJ scholar.google.com/ hl=ja as_sdt=2000 Transfer RNAs specific for Gln, Lys, and Glu from all organisms (except Mycoplasma) and organelles have a 2-thiouridine derivative (xm 5 s 2 U) as wobble nucleoside. These tRNAs read the A- and G-ending codons in the split codon boxes His/Gln, Asn/Lys, and Asp/Glu. In ... 2006 Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domain DG Waterman, M Ortiz-Lombardía, MJ Fogg, EV … - Journal of molecular …, 2006 - Elsevier http //scholar.google.co.jp/scholar?q=related j-_C2YkFA-IJ scholar.google.com/ hl=ja as_sdt=2000 as_ylo=1981 as_yhi=2010 ThiI is an enzyme responsible for the formation of the modified base S 4 U (4-thiouridine) found at position 8 in some prokaryotic tRNAs. This base acts as a sensitive trigger for the response mechanism to UV exposure, providing protection against its damaging effects. We ... Trafficking in persulfides delivering sulfur in biosynthetic pathways EG Mueller - Nature Chemical Biology, 2006 - nature.com http //scholar.google.co.jp/scholar?q=related ZzZgR5SebvcJ scholar.google.com/ hl=ja as_sdt=2000 The presence of sulfur in cofactors has been appreciated for over a century, but the trafficking and delivery of sulfur to cofactors and nucleosides is still not fully understood. In the last decade, great strides have been made toward understanding those processes and the ... Cell biology of molybdenum RR Mendel, F Bittner - Biochimica et Biophysica Acta (BBA)-Molecular …, 2006 - Elsevier http //scholar.google.co.jp/scholar?q=related C6ckangyps8J scholar.google.com/ hl=ja as_sdt=2000 The transition element molybdenum (Mo) is of essential importance for (nearly) all biological systems as it is required by enzymes catalyzing diverse key reactions in the global carbon, sulfur and nitrogen metabolism. The metal itself is biologically inactive unless it is complexed by ... The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like β-grasp domains biomedcentral.com [HTML]LM Iyer, AM Burroughs, L Aravind - Genome Biology, 2006 - biomedcentral.com http //scholar.google.co.jp/scholar?q=related UgYKXG9Yy80J scholar.google.com/ hl=ja as_sdt=2000 Ubiquitin (Ub)-mediated signaling is one of the hallmarks of all eukaryotes. Prokaryotic homologs of Ub (ThiS and MoaD) and E1 ligases have been studied in relation to sulfur incorporation reactions in thiamine and molybdenum/tungsten cofactor biosynthesis. However, there is no ... Mechanistic insights into sulfur relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions cell.com [HTML]Y Ikeuchi, N Shigi, J Kato, A Nishimura, T Suzuki - Molecular cell, 2006 - Elsevier http //scholar.google.co.jp/scholar?q=related 2Vsoqag0uDsJ scholar.google.com/ hl=ja as_sdt=2000 The wobble bases of bacterial tRNAs responsible for NNR codons are modified to 5-methylaminomethyl-2-thiouridine (mnm 5 s 2 U). 2-thio modification of mnm 5 s 2 U is required for accurate decoding and essential for normal cell growth. We identified five genes yhhP, ... 2005 Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs implications for the molecular … jbc.org [HTML]N Umeda, T Suzuki, M Yukawa, Y Ohya, H … - Journal of Biological …, 2005 - ASBMB http //scholar.google.co.jp/scholar?q=related l9eGdubEKOEJ scholar.google.com/ hl=ja as_sdt=2000 as_ylo=1981 as_yhi=2010 Human mitochondrial (mt) tRNA Lys has a taurine-containing modified uridine, 5-taurinomethyl-2-thiouridine ( m 5 s 2 U), at its anticodon wobble position. We previously found that the mt tRNA Lys , carrying the A8344G mutation from cells of patients with myoclonus ... l-Cysteine Desulfidase An [4Fe-4S] Enzyme Isolated from Methanocaldococcus jannaschii That Catalyzes the Breakdown of l-Cysteine into Pyruvate, Ammonia, and … SI Tchong, H Xu, RH White - Biochemistry, 2005 - ACS Publications http //scholar.google.co.jp/scholar?q=related QUO6D5wSaMQJ scholar.google.com/ hl=ja as_sdt=2000 as_ylo=1981 as_yhi=2010 A [4Fe-4S] enzyme that decomposes l-cysteine to hydrogen sulfide, ammonia, and pyruvate has been isolated and characterized from Methanocaldococcus jannaschii. The sequence of the isolated enzyme demonstrated that the protein was the product of the M. jannaschii ... Reconstitution of a new cysteine biosynthetic pathway in Mycobacterium tuberculosis nih.gov [HTML]KE Burns, S Baumgart, PC Dorrestein, H Zhai, … - J. Am. Chem. …, 2005 - ACS Publications http //scholar.google.co.jp/scholar?q=related 6UxhZ1K_8BAJ scholar.google.com/ hl=ja as_sdt=2000 A new pathway for cysteine biosynthesis has been elucidated in Mycobacterium tuberculosis. This pathway involves a protein-bound thiocarboxylate (CysO−SH) as the sulfide donor, similar to thiamin biosynthesis. Cysteine synthase M (CysM) catalyzes the addition ... 2004 Evidence for the physiological role of a rhodanese-like protein for the biosynthesis of the molybdenum cofactor in humans pnas.org [HTML]A Matthies, KV Rajagopalan, RR … - Proceedings of the …, 2004 - National Acad Sciences http //scholar.google.co.jp/scholar?q=related PpXEO3soBo0J scholar.google.com/ hl=ja as_sdt=2000 Recent studies have identified the human genes involved in the biosynthesis of the molybdenum cofactor. The human MOCS3 protein contains an N-terminal domain similar to the Escherichia coli MoeB protein and a C-terminal segment displaying similarities to the ... Ubiquitin-proteasome system umaryland.edu [PDF]S Fang, AM Weissman - Cellular and molecular life sciences, 2004 - Springer http //scholar.google.co.jp/scholar?q=related UwB61_LeFJAJ scholar.google.com/ hl=ja as_sdt=2000 Abstract. The capacity for exquisite regulation of ubiq- uitylation provides eukaryotic cells with a means to fine- tune both protein function and levels. This complex set of processes affects myriad proteins and potentially impacts all cellular processes. Ubiquitylation is brought about ... 2003 Attachment of the ubiquitin-related protein Urm1p to the antioxidant protein Ahp1p nih.gov [HTML]AS Goehring, DM Rivers, GF Sprague Jr - Eukaryotic cell, 2003 - Am Soc Microbiol http //scholar.google.co.jp/scholar?q=related NuIwzhoOL5cJ scholar.google.com/ hl=ja as_sdt=2000 Urm1p is a ubiquitin-related protein that serves as a posttranslational modification of other proteins. Urm1p conjugation has been implicated in the budding process and in nutrient sensing. Here, we have identified the first in vivo target for the urmylation pathway as the ... 2002 The rhodanese/Cdc25 phosphatase superfamily nih.gov [HTML]D Bordo, P Bork - EMBO reports, 2002 - nature.com http //scholar.google.co.jp/scholar?q=related OxriJBcqB5AJ scholar.google.com/ hl=ja as_sdt=2000 ... In this review, the rhodanese/Cdc25 phosphatase superfamily is analyzed. ... Figure 3 Neighbor-joining tree representing the rhodanese superfamily generated by CLUSTALW (correction for ... Catalytically active rhodanese and Cdc25 phosphatase domains The N- and C- ... 2001 A sulfurtransferase is required in the transfer of cysteine sulfur in the in vitro synthesis of molybdopterin from precursor Z in Escherichia coli jbc.org [HTML]S Leimkühler, KV Rajagopalan - Journal of Biological Chemistry, 2001 - ASBMB http //scholar.google.co.jp/scholar?q=related q8ya_wsSejkJ scholar.google.com/ hl=ja as_sdt=2000 It has been shown that conversion of precursor Z to molybdopterin (MPT) by Escherichia coli MPT synthase entails the transfer of the sulfur atom of the C-terminal thiocarboxylate from the small subunit of the synthase to generate the dithiolene group of MPT and that the moeB ... M ECHANISMS U NDERLYING U BIQUITINATION uky.edu [PDF]CM Pickart - Annual review of biochemistry, 2001 - Annual Reviews http //scholar.google.co.jp/scholar?q=related YIxzrFekkFQJ scholar.google.com/ hl=ja as_sdt=2000 as_ylo=2001 as_yhi=2001 Abstract The conjugation of ubiquitin to other cellular proteins regulates a broad range of eukaryotic cell functions. The high efficiency and exquisite selectivity of ubiquitination reactions reflect the properties of enzymes known as ubiquitin-protein ligases or E3s. An E3 recognizes its ... 2000 Evolution and function of ubiquitin-like protein-conjugation systems yale.edu [PDF]M Hochstrasser - Nature cell biology, 2000 - nature.com http //scholar.google.co.jp/scholar?q=related w2aIi7-UqxoJ scholar.google.com/ hl=ja as_sdt=2000 Cellular proteins are frequently adorned with chemical modifications that alter their physical — and, as a result, their physiological — properties. Among the most spectacular of these molecular appendages are grafts of other proteins or even polymeric chains of other proteins. The ... A protein conjugation system in yeast with homology to biosynthetic enzyme reaction of prokaryotes jbc.org [HTML]K Furukawa, N Mizushima, T Noda, Y … - Journal of Biological …, 2000 - ASBMB http //scholar.google.co.jp/scholar?q=related kWwdzGB67rIJ scholar.google.com/ hl=ja as_sdt=2000 Protein conjugation, such as ubiquitination, is the process by which the C-terminal glycine of a small modifier protein is covalently attached to target protein(s) through sequential reactions with an activating enzyme and conjugating enzymes. Here we report on a novel protein ... 1998 Cysteine Sulfinate Desulfinase, a NIFS-like Protein of Escherichia coli with Selenocysteine Lyase and Cysteine Desulfurase Activities Gene Cloning, Purification and … kyoto-u.ac.jp [PDF]N Esaki, T Kurihara, T Yoshimura, K … - ICR annual …, 1998 - repository.kulib.kyoto-u.ac.jp http //scholar.google.co.jp/scholar?q=related QtLum1tHQrQJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. Kyoto University KURENAI Kyoto University Research Information Repository Title Cysteine Sulfinate Desulfinase, a NIFS-like Protein of Escherichia coli with Selenocysteine Lyase and Cysteine Desulfurase Activities ... 1997 Cysteine Sulfinate Desulfinase, a NIFS-like Protein ofEscherichia coli with Selenocysteine Lyase and Cysteine Desulfurase Activities jbc.org [HTML]H Mihara, T Kurihara, T Yoshimura, K Soda, N … - Journal of Biological …, 1997 - ASBMB http //scholar.google.co.jp/scholar?q=related bOaL5q7FBDoJ scholar.google.com/ hl=ja as_sdt=2000 Selenocysteine lyase (EC 4.4.1.16) exclusively decomposes selenocysteine to alanine and elemental selenium, whereas cysteine desulfurase (NIFS protein) of Azotobacter vinelandii acts indiscriminately on both cysteine and selenocysteine to produce elemental sulfur and selenium ... 1991 Characteristics of Nicotiana tabacum nitrate reductase protein produced in Saccharomyces cerevisiae. nih.gov [PDF]HN Truong, C Meyer, F Daniel-Vedele - Biochemical Journal, 1991 - ncbi.nlm.nih.gov http //scholar.google.co.jp/scholar?q=related 8oijnWbQUp4J scholar.google.com/ hl=ja as_sdt=2000 as_ylo=1981 as_yhi=2010 INTRODUCTION Tobacco nitrate reductase (NR) (EC 1.6.6.1) is a homodimeric enzyme that reduces nitrate to nitrite in the presence of NADH (NADH NR activity). Each of its subunits contains three domains carrying respectively the prosthetic groups FAD, haem (cytochrome b-557) ... UBA 1 an essential yeast gene encoding ubiquitin-activating enzyme. nih.gov [PDF]JP McGrath, S Jentsch, A Varshavsky - The EMBO journal, 1991 - ncbi.nlm.nih.gov http //scholar.google.co.jp/scholar?q=related qFlUGfxF0asJ scholar.google.com/ hl=ja as_sdt=2000 The EMBO Journal vol.10 no.1 pp.227-236, 1991 ... UBA 1 an essential yeast gene encoding ubiquitin- ... John P.McGrath, Stefan Jentsch and Alexander Varshavsky ... Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA Present ...
https://w.atwiki.jp/metalmetabo/pages/31.html
- visitors The small world inside large metabolic networks royalsocietypublishing.org [PDF]A Wagner, DA Fell - … of the Royal Society of London …, 2001 - rspb.royalsocietypublishing.org http //scholar.google.com/scholar?q=related RzgGd87o6owJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. doi 10.1098/rspb.2001.1711 , 1803-1810 268 2001 Proc. R. Soc. Lond. B Andreas Wagner and David A. Fell The small world inside large metabolic networks References http //rspb.royalsocietypublishing.org/content/268/1478/1803#related-urls Article cited in ... In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data vcu.edu [PDF]JS Edwards, RU Ibarra, BO Palsson - Nature biotechnology, 2001 - nature.com http //scholar.google.com/scholar?q=related E0x6EPMqz7kJ scholar.google.com/ hl=ja as_sdt=2000 ... J. Theor. Biol. 203, 249–83 (2000). | Article | PubMed | ISI | ChemPort |; Schilling, CH, Schuster, S., Palsson, BO Heinrich, R. Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15, 296–303 (1999). ... The small world of metabolism stanford.edu [PDF]DA Fell, A Wagner - Nature Biotechnology, 2000 - nature.com http //scholar.google.com/scholar?q=related vJDOQbOxaVoJ scholar.google.com/ hl=ja as_sdt=2000 ... propositions. Top of page References. Schilling, CH, Schuster, S., Palsson, BO Heinrich, R. Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15, 296–303 (1999). ... Metabolic pathways in the post-genome era psu.edu [PDF]JA Papin, ND Price, SJ Wiback, DA Fell, BO … - Trends in Biochemical …, 2003 - Elsevier http //scholar.google.com/scholar?q=related yCUSHfucTk8J scholar.google.com/ hl=ja as_sdt=2000 ... All possible flux distributions of a metabolic network lie within the cone circumscribed by the pathways. View Within Article. 1. History of network-based metabolic pathway analyses. Network-based metabolic pathway analysis has a relatively short history. ... The Escherichia coli MG1655 in silico metabolic genotype its definition, characteristics, and capabilities pnas.org [HTML]JS Edwards, BO Palsson - … of Sciences of the United States …, 2000 - National Acad Sciences http //scholar.google.com/scholar?q=related ylmoiEQjy08J scholar.google.com/ hl=ja as_sdt=2000 ... These methods include approaches such as metabolic control analysis (3, 4), flux balance analysis (FBA) (5–7), metabolic pathway analysis (8–11, 69), cybernetic modeling (12), biochemical systems theory (13), temporal decomposition (14), and so on. ... Analysis of metabolic capabilities using singular value decomposition of extreme pathway matrices nih.gov [HTML]ND Price, JL Reed, JA Papin, I Famili, BO Palsson - Biophysical journal, 2003 - Elsevier http //scholar.google.com/scholar?q=related vBbGDsA7avcJ scholar.google.com/ hl=ja as_sdt=2000 Phylogenetic analysis based on genome-scale metabolic pathway reaction content silicobio.com [PDF]SH Hong, TY Kim, SY Lee - Applied microbiology and biotechnology, 2004 - Springer http //scholar.google.com/scholar?q=related 2MW2dxoUfOIJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. Appl Microbiol Biotechnol (2004) 65 203–210 DOI 10.1007/s00253-004-1641-3 GENOMICS AND PROTEOMICS SH Hong . TY Kim . SY Lee Phylogenetic analysis based on genome-scale metabolic pathway reaction content ... Extreme pathway lengths and reaction participation in genome-scale metabolic networks cshlp.org [HTML]JA Papin, ND Price, BØ Palsson - Genome research, 2002 - genome.cshlp.org http //scholar.google.com/scholar?q=related o1ZwGAWEzSUJ scholar.google.com/ hl=ja as_sdt=2000 ... Schilling CH,; Schuster S.,; Palsson BO,; Heinrich R. (1999) Metabolic pathway analysis Basic concepts and scientific applications in the post-genomic era. Biotech. Prog. 15 296–303. ... Flux coupling analysis of genome-scale metabolic network reconstructions cshlp.org [HTML]AP Burgard, EV Nikolaev, CH Schilling, CD … - Genome …, 2004 - genome.cshlp.org http //scholar.google.com/scholar?q=related IXLhT3n9KwQJ scholar.google.com/ hl=ja as_sdt=2000 Metabolic modeling of microbial strains in silico ru.nl [PDF]MW Covert, CH Schilling, I Famili, JS Edwards, … - Trends in Biochemical …, 2001 - Elsevier http //scholar.google.com/scholar?q=related pjh6sWp3MRMJ scholar.google.com/ hl=ja as_sdt=2000 ... References. Schilling, CH et al., Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15, pp. 296–303. Schilling, CH et al., Towards metabolic phenomics analysis of genomic data using flux balances. Biotechnol. ...
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【Tags Akuno-P Haku Yowane Miku tB tD tG S】 Original Music Title 白ノ娘 English music title Daughter of White / Girl of White Romaji music title Shiro no Musume Music Lyrics written, Voice edited by mothy \ 悪ノP(Akuno-P) Music arranged by mothy \ 悪ノP(Akuno-P) Singer 初音ミク (Hatsune Miku) as 弱音ハク (Haku Yowane) This song is included in "Aku no Musume" series. The English song title given by the author is "Bystander", which is not literal translation of the Japanese title. Click here for the Japanese Lyrics English Lyrics (translated by Kanannon)： "I m sorry for being alive" A habit I keep on saying I ve always been softly complaining A meaningless existence Everybody in my village has beautiful green hair I m an outcast with white hair that no one has Deep in the forest stands an old tree I always come here alone and pray to god Living all alone Is very sad I just want someone, anyone To be my friend I met her right near the old tree It began when I saved her while she was unconscious on the ground Before long, we became close But that girl and I are very different She had the most beautiful green hair in the village She was loved by everyone with her kind voice and smile Why are you being so kind to me? Are you just pitying me because I m so inferior to you? You gently hold me and say to me as I was cringing "You re the most wonderful person I met" I cried in her arms Even if the entire world laughed and despised me I had a person who needed me That s all I need to be happy We ran away from the village and started living in a city Even though everything seems unfamiliar, it s okay because we re together We became servants under a wealthy merchant lady It s a job we chose in order to live One day, a blue haired man came by the mansion Their encounter twisted everything A prince from across the ocean. He fell deeply in love with her. So much that he rejected the neighboring queen s marriage proposal The land was engulfed in war The queen gave the order "Seek out every green-haired woman and kill them" Everyone, everyone was gone Except for myself with the white hair I wish that I could ve died in your place Why...why... "I m sorry for being alive" A habit I keep on saying I ve always been softly complaining A boring existence I started living in a small chapel near the harbor I heard a rumor that the queen died in the revelation I met her near the chapel It began when I saved her while she was unconscious on the ground Before long, we became close But that girl and I are very different In the empty confession box at night I overheard her confession Ah, how can this be She is indeed...The daughter of Evil In a harbor at the edge of town Stands a lonely girl I come up from behind her I take a knife out of my pocket I point it at her back And swing it up There s something I have to apologize to you I couldn t take your revenge She is the girl I was back then A very, very lonely girl Living all alone Is very sad That girl who couldn t do anything Improved a little in her cooking The brioche she made for snack Was baked very well At that moment, at the harbor I saw an illusion I wonder who that boy was? Romaji lyrics (transliterated by motokokusanagi2009)： "ikite ite gomen nasai" itsu no ma nika kuchi guse yowane bakari haite ita tsumaranu dake no jinsei mura no hito tachi wa mina kirei na midori no kami nakama hazure no watashi hito to chigau shiroi kami mori no oku de hisoka ni sobie tatsu sennen ju watashi wa koko de hitori kami ni negai o kaketa kodoku ni iki tsuzukeru koto sore wa totemo samishī dare demo ī watashi no tomodachi ni natte hoshī kanojo to deatta nowa senen ju no sugu soba taorete ita kanojo o tasuketa noga hajimari itsu no ma nika futari wa totemo nakayoku natta dakedo watashi to kanojo nani mo kamo ga chigatta mura no naka no dare yori kirei na midori no kami sono yasashī koe to egao dare kara mo ai sareta dōshite konna watashi nimo yasashiku shite kureru no? jibun yori otoru onna o awaren deru tsumori nano? hikutsu na watashi o daki shimete kanojo wa sasayaita "anata wa dare yori suteki na hito yo" namida ga koboreta tatoe sekai no subete no hito ga watashi o sagesumi warattemo hitsuyō to shite kureru hito ga iru sore dake de shiawase datta futari de mura o tobi dashite machi de kurashi hajimeta funare na seikatsu demo issho nara daijōbu yūfuku na shōnin no fujin no shiyōnin ikiru tame ni eranda watashi tachi no shigoto aru hi yashiki de mikaketa aoi kami no yasa otoko aitsu to kanojo no deai ga subete o kuru waseta umi no mukō no kuni no ō kare wa kanojo o fukaku aishi tonari no kuni no ōjo no kyūkon o kobanda kuni wa senka ni tsutsu mareta ōjo ga kudashita meirei "midori no kami no onna wa subete koroshite simai nasai" minna minna inaku natte shimatta shiroi kami no watashi igai kanojo no kawari ni watashi ga shine ba yokatta noni dōshite dōshite "ikite ite gomen nasai" itsu no ma nika kuchi guse yowane bakari haite ita tsumaranu dake no jinsei minato machi no kyōkai arata ni kurashi hajimeta kakumei de ōjo ga shinda to kaze no uwasa de kīta kanojo to deatta nowa kyōkai no sugu soba taorete ita kanojo o tasuketa noga hajimari itsu no ma nika futari wa totemo nakayoku natta dakedo watashi to kanojo nani mo kamo ga chigatta dare mo inai yoru no zange shitsu gūzen kīte shimatta kanojo no kokuhaku ah nanto iu koto deshō kanojo wa masa ni aku no musume machi hazure no chīsa na minato hitori tatazumu ano ko haigo kara chikazuku watashi futokoro kara knife tori dashi te ōjo no senaka ni muke te furi ageta anata ni ayamara nakereba ike nai koto ga aru no watashi kekkyoku anata no kataki wa tore nakatta ano ko wa mukashi no watashi totemo totemo kodoku na hito hitori de iki tsuzukeru koto sore wa totemo samishī nani mo deki nakatta ano ko sukoshi ryōri ga umaku natta kyōno oyatsu no Brioche tottemo umaku yake teru ano toki ano umibe de isshun mieta genkaku ano shōnen wa ittai dare datta no kashira? [mothy, Akuno-P, AkunoP]